ChemInform Abstract: Free-Radical Oxidation of para-Substituted Phenols by Hypervalent tert- Butylperoxyiodane and tert-Butyl Hydroperoxide: Synthesis of 4-(tert- Butylperoxy)-2,5-cyclohexadien-1-ones.

✍ Scribed by M. OCHIAI; A. NAKANISHI; A. YAMADA

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199736058

✦ Synopsis

Free-Radical Oxidation of para-Substituted Phenols by Hypervalent tert-Butylperoxyiodane and tert-Butyl Hydroperoxide: Synthesis of 4-(tert-Butylperoxy)-2,5-cyclohexadien-1-ones.

-The selective radical oxidation of phenolic compounds by tert-butylperoxyiodane, which undergoes homolytic cleavage of the hypervalent tBuO-O-I bond at room temperature, proceeds under mild conditions yielding cyclohexadienone products.