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ChemInform Abstract: Free Radical Generation by Reduction of Ketone Tosylhydrazones.

โœ Scribed by Douglass F. Taber; Pramod V. Joshi


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
33
Category
Article
ISSN
0931-7597

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Alkoxy-Directed Radical Reductions of Ketones Using Trichlorosilane. -A new highly diastereoselective reduction of ฮฑ-hydroxy ketones with inexpensive HSiCl 3 gives predominantly anti 1,2-diols which are converted to ketals (III) and (V) for better separation of diastereomeric mixtures. Other silane