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ChemInform Abstract: Formal Nucleophilic Substitution of Bromocyclopropanes with Amides en route to Conformationally Constrained β-Amino Acid Derivatives.

✍ Scribed by Anthony R. Prosser; Joseph E. Banning; Marina Rubina; Michael Rubin

Publisher: John Wiley and Sons
Year: 2010
Weight: 44 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201102069

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✦ Synopsis

Abstract

A wide range of trans‐β‐aminocyclopropane carboxylic acid derivatives is prepared with the highest yields being observed for the 4‐(trifluoromethyl)‐ or 3,5‐bis‐(trifluoromethyl) benzoic acid amides.

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