ChemInform Abstract: Fluorocyclization of 2,5-Tetrahydrofurandicarboxylic and 2,3,4,5-Tetrahydrofurantetracarboxylic Acids with Sulfur Tetrafluoride Leading to Bicyclic and Tricyclic Fluoroethers.

✍ Scribed by Y. M. PUSTOVIT; W. DMOWSKI; V. NAZARETIAN

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 35 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199814103

✦ Synopsis

Fluorocyclization of 2,5-Tetrahydrofurandicarboxylic and 2,3,4,5-Tetrahydrofurantetracarboxylic Acids with Sulfur Tetrafluoride Leading to Bicyclic and Tricyclic Fluoroethers. -Treatment of acids (I), (IV), and (VII) with SF 4 causes cyclization to occur via two carboxylic groups in cis-2,5-positions, giving the corresponding fluorinated, six-membered dioxane rings. This 1,3-cyclization competes effectively with the conversion of carboxylic groups into trifluoromethyl groups.

-(PUSTOVIT, Y. M.;