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ChemInform Abstract: First Efficient Syntheses of 1-, 4-, and 5-Caffeoylquinic Acid.

โœ Scribed by Michael Sefkow; Alexandra Kelling; Uwe Schilde


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
33
Category
Article
ISSN
0931-7597

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First Efficient Syntheses of 1-, 4-, and
โœ Michael Sefkow; Alexandra Kelling; Uwe Schilde ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 387 KB ๐Ÿ‘ 2 views

Efficient synthesis of 1-, 4-, and 5-caffeoylquinic acid was achieved in three or four steps with suitably protected quinic acid precursors, in overall yields of 41%, 36%, and 60% [from quinic acid (1)]. 1-Caffeoylquinic acid was prepared by esterification of acetone quinide 7 with caffeoyl chloride