ChemInform Abstract: Facile Synthesis of
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T. FUJISAWA; T. ITO; K. FUJIMOTO; M. SHIMIZU; H. WYNBERG; E. G. J. STARING
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Article
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2010
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John Wiley and Sons
⚖ 33 KB
Facile Synthesis of (S)-β-Hydroxy-β-trichloromethylated Aromatic Ketones by the Regioselective Ring Cleavage of Chiral β-Trichloromethyl-β-propiolactone under the Friedel-Crafts Conditions. -The enantiopure lactone (I) undergoes regioselective Friedel-Crafts acylation with a variety of arenes to giv