ChemInform Abstract: Facile Synthesis of (+)-α-Allokainic Acid via Pd-Catalyzed Hydrogenolysis of Allyl Acetate Derived from trans-4-Hydroxy-L-proline.

ChemInform Abstract: New Amino Acids Der

ChemInform Abstract: New Amino Acids Derived from L-Pyroglutamic Acid: Synthesis of trans-4-Benzyl-cis-5-phenyl-L-proline, L-α-(2-Benzyl-3-phenylpropyl)-glycine and L-α-(3-Phenylpropyl)-glycine.

✍ J. VAN BETSBRUGGE; W. VAN DEN NEST; P. VERHEYDEN; D. TOURWE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 2 views

Pyroglutamic acid derivative (I) is proved to be an excellent chiral starting compound for the synthesis of title amino acids (IX), (X), and (V). The syntheses are based on a combination of methods previously used for the preparation of 4-and 5-substituted prolines. These methods are the ring openin