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ChemInform Abstract: Facile Synthesis of Anxiolytic Buspirone (V).

✍ Scribed by Jie Mou; Zhi-Min Zong; Xian-Yong Wei


Publisher
John Wiley and Sons
Year
2008
Weight
27 KB
Volume
39
Category
Article
ISSN
0931-7597

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Synthesis of the anxiolytic agent [14C]
✍ Samuel J. Bonacorsi Jr; Richard C. Burrell; George M. Luke; Jeffrey S. DePue; J. πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 French βš– 124 KB

## Abstract A reliable synthesis of ^14^C labeled 6‐hydroxy‐buspirone is described. The molecule belongs to a unique class of compounds with the potential for anxiolytic activity. A radiolabeled analog was prepared to support the development of 6‐hydroxy‐buspirone. Specifically, a labeled variant w