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ChemInform Abstract: Facile Selective Detritylation of 5′-Primary Alcohols of Pyrimidine Nucleosides Using Tetra-n-butylammonium Peroxydisulfate.

✍ Scribed by S. G. YANG; D. H. LEE; Y. H. KIM

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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Facile selective detritylation of 5′-pri
Facile selective detritylation of 5′-primary alcohols of pyrimidine nucleosides using tetra-n-butylammonium peroxydisulfate
✍ Seung Gak Yang; Dong Hoon Lee; Yong Hae Kim 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 1 views

Tetra-n-butylammonium peroxydisulfate has been found to be a good deprotecting reagent for removal of the trityl group: Treatment of 5Ј-O-dimethoxytrityl uridine or thymidine with tetra-n-butylammonium peroxydisulfate gave the corresponding dedimethoxytritylated nucleosides in excellent yields under