ChemInform Abstract: Facile Method for the Combinatorial Synthesis of 2,2-Disubstituted Quinazolin-4(1H)-one Derivatives Catalyzed by Iodine in Ionic Liquids.

✍ Scribed by Xiang-Shan Wang; Ke Yang; Jie Zhou; Shu-Jiang Tu

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 33 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201052169

✦ Synopsis

Facile Method for the Combinatorial Synthesis of 2,2-Disubstituted Quinazolin--4(1H)-one Derivatives Catalyzed by Iodine in Ionic Liquids. -2-Aminobenzamides and aliphatic, aromatic, cyclic, and heterocyclic ketones as well as cyclohexane-1,4-diones give the desired quinazolinones in high yields (73 examples). -(WANG*, X.