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ChemInform Abstract: Facile Construction of the Tricyclo[5.2.1.01,5]decane Ring System by Intramolecular Double Michael Reaction: Highly Stereocontrolled Total Synthesis of (.+-.)-8,14-Cedranediol and (.+-.)-8,14-Cedranoxide.

✍ Scribed by Masataka Ihara; Kei Makita; Kiyosei Takasu


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Facile Construction of the Tricyclo[5.2.1.0 1,5 ]decane Ring System by Intramolecular Double Michael Reaction: Highly Stereocontrolled Total Synthesis of (±)-8,14-Cedranediol and (±)-8,14-Cedranoxide. -Intramolecular double Michael reaction of cyclopentenone (I) is the key step in the synthesis of racemic cedranediol (III) and cedranoxide (IV) from 4-(1-cyclopenten-1-yl)morpholine. -(IHARA, MASATAKA; MAKITA, KEI;