✦ LIBER ✦
ChemInform Abstract: Expeditious One-Pot, Four-Step Preparation of 2-t-Butoxycarbonyl-6-hydroxy-1,2,3,4-tetrahydroisoquinoline and an Improved Conversion to Its 6-Cyano Derivative.
✍ Scribed by David W. Gordon; Carol A. Bains
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
Title compound (IV) is obtained in multigram quantities by a novel sequential one‐pot procedure comprising imination/Pictet—Spengler cyclization/demethylation/Boc‐protection.