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ChemInform Abstract: Excellent Acceleration of the Diels—Alder Reaction by Microwave Irradiation for the Synthesis of New Fluorine-Substituted Ligands of NMDA Receptor.

✍ Scribed by Shigeki Sasaki; Nobuyasu Ishibashi; Tshuneo Kuwamura; Hiromi Sano; Masaki Matoba; Tohru Nisikawa; Minoru Maeda

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Excellent Acceleration of the Diels-Alder Reaction by Microwave Irradiation for the Synthesis of New Fluorine-Substituted Ligands of NMDA Receptor.

-The Diels-Alder reaction to form quinolizinium derivatives of type (V) or (VI) is optimized in reaction time using a microwave procedure. The short reaction time can be achieved by adding water. The new derivatives show binding affinity towards NMDA receptors. -(SASAKI,

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