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ChemInform Abstract: Eu(fod)3-Catalyzed Rearrangement of Allylic Esters Possessing a Chelating Site. Application to Enediyne Synthesis.

✍ Scribed by Wei-Min Dai; Mavis Yuk Ha Lee


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Eu(fod) 3 -Catalyzed Rearrangement of Allylic Esters Possessing a Chelating Site. Application to Enediyne Synthesis.

-1,2-Dialkynyl-3-alkyl or 3-aryl allylic esters (I) possessing a chelating site undergo Eu(fod) 3 -catalyzed rearrangement to yield cis-enediynes (II) exclusively (13 examples). The chelating site is responsible for a remarkably enhanced reactivity.