ChemInform Abstract: Ethyl 3-Iodo-4,4,4-trifluoro-2(Z)-butenoate: Regio- and Stereospecific Preparation and Palladium-Catalyzed Reaction with Terminal Alkynes.
β Scribed by F.-L. QING; Y. ZHANG
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Ethyl 3-Iodo-4,4,4-trifluoro-2(Z)-butenoate: Regio-and Stereospecific Preparation and Palladium-Catalyzed Reaction with Terminal Alkynes.
-The title compound (II), regio-and stereoselectively prepared from the alkyne (I), undergoes the Sonogashira reaction with terminal alkynes. In the presence of catalytic PdCl2(PPh3)2 the enynes (IV) are obtained in good yields.
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