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ChemInform Abstract: Ethyl 3-Iodo-4,4,4-trifluoro-2(Z)-butenoate: Regio- and Stereospecific Preparation and Palladium-Catalyzed Reaction with Terminal Alkynes.

✍ Scribed by F.-L. QING; Y. ZHANG


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Ethyl 3-Iodo-4,4,4-trifluoro-2(Z)-butenoate: Regio-and Stereospecific Preparation and Palladium-Catalyzed Reaction with Terminal Alkynes.

-The title compound (II), regio-and stereoselectively prepared from the alkyne (I), undergoes the Sonogashira reaction with terminal alkynes. In the presence of catalytic PdCl2(PPh3)2 the enynes (IV) are obtained in good yields.


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ChemInform Abstract: Palladium-Catalyzed
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