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ChemInform Abstract: Enzyme-Catalyzed Formation of (S)-Cyanohydrins Derived from Aldehydes and Ketones in a Biphasic Solvent System.

✍ Scribed by Herfried Griengl; Norbert Klempier; Peter Poechlauer; Michael Schmidt; Nongyuan Shi; Antonia A. Zabelinskaya-Mackova

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Enzyme-Catalyzed Formation of (S)-Cyanohydrins Derived from Aldehydes and Ketones in a Biphasic Solvent System.

-The bioagent-catalyzed synthesis of (S)-cyanohydrins is well established. By employing a vigorously stirred two-phase reaction system, chiral cyanohydrins from aliphatic, unsaturated, aromatic and heteroaromatic aldehydes such as (IV) and from ketones such as (I) could be obtained in good yield and optical purity. -

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