ChemInform Abstract: Enantioselective Total Synthesis of (+)-Isoboonein.

✍ Scribed by Masahiro Tada; Sayako Inoue; Takao Miki; Shin-ichi Onogi; Jun-ichi Kaminaga; Junko Hiraoka; Yoshikazu Kitano; Kazuhiro Chiba

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199912194

✦ Synopsis

Enantioselective Total Synthesis of (+)-Isoboonein.

-Starting from the known optically active diol (I), derived via an asymmetric Diels-Alder reaction of dimethyl fumarate with cyclopentadiene, the key intermediate (II) is synthesized via a known approach applied to the racemic series. Further selective transformations lead to the title compound (VII). -(TADA, MASAHIRO;