ChemInform Abstract: Enantioselective Total Synthesis of Fumonisin B2.
β Scribed by Y. SHI; L. F. PENG; Y. KISHI
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 40 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Enantioselective Total Synthesis of Fumonisin B 2 .
-The title compound (XIV) is a representative member of a class of mycotoxins known to exhibit a wide range of biological activities. Its first total synthesis is accomplished in a convergent manner from the fragments (VI), (XII), and the tricarballylic acid segment. The preparation of building blocks (VI) and (XII) is described. -(SHI, Y.;
π SIMILAR VOLUMES
Enantioselective Total Synthesis of Reveromycin B. -The crucial steps to synthesize the title compound (VIII) include a modified Negishi coupling of alkyne (I) with iodide (II) and the Kishi-Nozaki coupling of aldehyde (IV) with iodide (V). The former coupling is more efficient and superior as compa
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