## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
ChemInform Abstract: Enantioselective Synthesis of α-Amino Acids from Nitroalkenes.
✍ Scribed by S. SABELLE; D. LUCET; T. LE GALL; C. MIOSKOWSKI
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Enantioselective Synthesis of α-Amino Acids from Nitroalkenes.
-Careful oxidation of the addition products (I) of (R)-4-phenyl-2-oxazolidine and nitroalkenes yields the acids (II) which can be easily cleaved to D-α-amino acids of high optical purity.
📜 SIMILAR VOLUMES
The diastereoselective synthesis of α-amino esters from the glycine ester (I) employing the sulfonamides (II) as chiral auxiliaries works well for α-alkylation with methyl iodide. Ethylation, allylation, and benzylation proceeds with fair stereoselectivity, but pure diastereomers can be obtained by
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v