ChemInform Abstract: Enantioselective Synthesis of Key Intermediate (II) of Levofloxacin Using Microbial Resolution.
β Scribed by Akihiko Miyadera; Akihiro Imura
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Microbially-Aided Preparation of (S)-2-Methoxycyclohexanone Key Intermediate in the Synthesis of Sanfetrinem. -It is shown that the enantiomerically pure (S)-carbinol (I), obtained by baker's yeast-mediated reduction of 2-benzylcyclohexanone, can be transformed efficiently into the title ketone (S)