ChemInform Abstract: Enantioselective Synthesis of Cyclic Carbamimidates via a Three-Component Reaction of Imines, Terminal Alkynes, and p-Toluenesulfonylisocyanate Using a Monophosphine Gold(I) Catalyst.

✍ Scribed by Matthew J. Campbell; F. Dean Toste

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 55 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201142123

✦ Synopsis

Abstract

In all cases, a mixture of five‐ and six‐membered rings is obtained favoring oxazole derivatives (ratio 1,6:1 up to ≥ 20:1).