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ChemInform Abstract: Enantioselective Synthesis of 2,3-Disubstituted Piperidines from (S)-Methylpyroglutamate.

โœ Scribed by Olivier Calvez; Angele Chiaroni; Nicole Langlois


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: An Enantioselective
โœ S. CHACKALAMANNIL; Y. WANG ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 1 views

An Enantioselective Route to trans-2,6-Disubstituted Piperidines. -It is shown that trans-2,6-disubstituted piperidines can be prepared enantioselectively via (3 + 2) nitrone cycloaddition. This method is applied to the synthesis of the fire ant venom alkaloid (+)-solenopsin-A (IX). -