β Scribed by Dawei Ma; Jianhua Zhang
No coin nor oath required. For personal study only.
Enantioselective Syntheses of Tussilagine and Isotussilagine.
-LDA-mediated addition of chiral benzylamine (I) to methyl pyruvate (II) generates the separable diastereomers (III) and (IV). The latter can be conveniently transformed to tussilagine (VIII) by lactam formation and following Mitsunobu reaction to the bicyclic product (VI) as key steps. In a similar manner, isotussilagine is obtained from the adduct (III). -(MA, DAWEI;
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v