ChemInform Abstract: Enantioselective Rearrangement of Proline Sulfonamides: An Easy Entry to Enantiomerically Pure α-Aryl Quaternary Prolines.

✍ Scribed by Francesca Foschi; Dario Landini; Vittoria Lupi; Voichita Mihali; Michele Penso; Tullio Pilati; Aaron Tagliabue

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201103201

✦ Synopsis

Abstract

A highly enantioselective rearrangement of proline‐derived sulfonamides proceeds in the presence of base to give α‐arylprolines with a quaternary stereocenter in up to 96% optical purity.