ChemInform Abstract: Enantioselective Protonation of Prochiral Enolates with Chiral Imides.
β Scribed by A. YANAGISAWA; T. KIKUCHI; T. KURIBAYASHI; H. YAMAMOTO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 40 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Diastereoselective Protonation of Chiral Enolate with Chiral Imides. -Protonation of the lithium enolate (I) of (-)-menthone by chiral imides such as the (R)-imide of conditions (A) generates mainly the cis ketone (III). The selectivity of this process can be completely reversed by using the corres
Dimeric [Ca(OCtBu,) ,] is synthesized from 2a and HOCIBU, by analogy to Equation (c); colorless crystals, moderately soluble in n-pentane. readily soluble in toluene and diethyl ether. Warming under high vacuum (185'Ci mbar) gives a moderate yield of trimeric [Ca(OCHtBu,),] as a colorless sublimate