ChemInform Abstract: Enantioselective Preparation of the Stereoisomers of 4-Methylheptan-3-ol Using Candida antarctica Lipase B.

✍ Scribed by C. R. UNELIUS; J. SANDELL; C. ORRENIUS

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199837277

✦ Synopsis

Enantioselective Preparation of the Stereoisomers of 4-Methylheptan-3-ol Using Candida antarctica Lipase B.

-The four stereoisomers of 4-methylheptan-3-ol (V), components of the aggregation pheromone of some bark beetles, are prepared through fractional crystallization of a mixture of their racemic dinitrobenzoates (III) and (IV), followed by hydrolysis and enantioselective, lipase-mediated transesterification.

-(UNELIUS, C. R.;