ChemInform Abstract: Enantioselective Mannich Reaction of a Highly Reactive Horner—Wadsworth—Emmons Reagent with Imines Catalyzed by a Bifunctional Thiourea.

✍ Scribed by Depeng Zhao; Dongxu Yang; Yijie Wang; Yuan Wang; Linqing Wang; Lijuan Mao; Rui Wang

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 42 KB
• Volume: 43
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201202044

✦ Synopsis

Abstract

N‐Acyl pyrrole phosphonates (II) are highly reactive nucleophiles for the asymmetric Horner—Wadsworth—Emmons reaction.