The enantioselective formation of C À C bonds is an area of intense research. [1,2] The asymmetric addition of alkynyl reagents to aldehydes is very useful for the synthesis of chiral secondary propargyl alcohols, which are important building blocks for many chiral organic compounds. [3] Several stu
ChemInform Abstract: Enantioselective Addition of Phenylacetylene to Aldehydes Catalyzed by a D-Glucosamine-Derived Sulfonamide—Titanium Complex.
✍ Scribed by Tomasz Bauer; Slawomir Smolinski; Przemyslaw Gawel; Janusz Jurczak
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 32 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A series of β‐sulfonamide alcohol ligands were synthesized from L‐phenylalanine. Titanium complexes of these compounds were used to catalyze the asymmetric addition of phenylacetylene to a number of aldehydes. When the conditions were optimized, 20 mol % of ligand **8a** catalyzed the r
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v