ChemInform Abstract: Enantioselective Acyclic Stereoselection under Catalyst (Promoter) Control. Part 5. Towards a Practical Synthesis of Acutiphycin. Highly Stereoselective Synthesis of C10-epi Seco Acid Derivative via Reaction Paths Shortened by Using a Series of Chiral Oxazaborolidinone-Promoted Aldol Reactions.

✍ Scribed by Mostofa Abu Hena; Chul-Sa Kim; Michio Horiike; Syun-ichi Kiyooka

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 36 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199921228

✦ Synopsis

Enantioselective Acyclic Stereoselection under Catalyst (Promoter) Control. Part 5. Towards a Practical Synthesis of Acutiphycin. Highly Stereoselective Synthesis of C10-epi Seco Acid Derivative via Reaction Paths Shortened by Using a Series of Chiral Oxazaborolidinone-Promoted Aldol Reactions.

-A series of five oxazaborolidine-promoted aldol reactions is used in the enantioselective synthesis of (XV), an acyclic seco acid derivative of acutiphycin. -(HENA,