๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

ChemInform Abstract: Enantiomerically Pure 2-Piperazinemethanols as Novel Chiral Ligands of Oxazaborolidine Catalysts in Enantioselective Borane Reductions.

โœ Scribed by Tsutomu Inoue; Daisuke Sato; Kenichi Komura; Shinichi Itsuno

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

โœฆ Synopsis

Enantiomerically Pure 2-Piperazinemethanols as Novel Chiral Ligands of Oxazaborolidine Catalysts in Enantioselective Borane Reductions.

-The asymmetric borane reduction of aromatic ketones or oxime ethers in the presence of chiral in situ generated oxazaborolidine catalysts is described. The preferred absolute configuration of the product depends on the N-sulfonyl substituent in the 2-piperazinemethanol employed. Best results are obtained with the examples (I)-(III). -(INOUE, TSUTOMU; SATO,

๐Ÿ“œ SIMILAR VOLUMES

ChemInform Abstract: Chiral Oxazaborolid
ChemInform Abstract: Chiral Oxazaborolidines Bearing a 1- or 2-Naphthylmethyl Group as Catalysts for the Enantioselective Borane Reduction of Ketones: Experimental and Quantum Chemical Calculations.
โœ Z. SHEN; W. HUANG; J. FENG; Y. ZHANG ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB

Chiral Oxazaborolidines Bearing a 1-or 2-Naphthylmethyl Group as Catalysts for the Enantioselective Borane Reduction of Ketones: Experimental and Quantum Chemical Calculations. -Two new catalysts are employed in the asymmetric borane reduction of ketones. The results are verified by quantum chemica