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ChemInform Abstract: Enantiomerically Pure 2-Alkyl and 2,3-Dialkylaziridines from 2-Sulfinylimines.

✍ Scribed by Jose L. Garcia Ruano; Antonio Lorente; Jesus H. Rodriguez Ramos


Book ID
101878267
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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Enantiomerically pure 2-alkyl and 2,3-di
✍ JosΓ©L. GarcΓ­a Ruano; Antonio Lorente; JesΓΊs H. RodrΓ­guez Ramos πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 269 KB

A new entry to optically pure aziridines from N-p-methoxyphenyl derivatives of 2-p-tolylsulfinylketimines is reported. The highly stereoselective reduction of the imines with DIBAL-H/ZnX2 yielded the corresponding sulfinyl amines, which can be transformed into the N-Cbz derivatives through a two-ste