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ChemInform Abstract: Enantiodivergent Synthesis of Both Enantiomers of the Macrocyclic Lactone Lasiodiplodin.

✍ Scribed by F. BRACHER; B. SCHULTE


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: An Enantiodivergent
✍ F. BRACHER; B. SCHULTE πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB

An Enantiodivergent Synthesis of Both Enantiomers of the Macrocyclic Lactone Curvularin. -An enantiodivergent synthesis of curvularin (S)-(IX) and its enantiomer is presented based on the esterification of key intermediate (S)-(V) under either retention or inversion of the chiral center leading to