ChemInform Abstract: Enantioconservative Synthesis of Polysubstituted Pyrimido[4,5-b]azepines.

✍ Scribed by Britta Gerig; Ulrich Girreser; Martin Schuett; Dieter Heber

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 26 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201043173

✦ Synopsis

Abstract

The three‐step synthesis of the title compounds, which have a high potential as adenosine receptors, is based on a Dieckmann cyclization of racemic cyano esters (V) and chiral cyano ester (IX).