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ChemInform Abstract: Efficient Synthesis of 2-Methylaminothiazolines via Mitsunobu Reaction of N-(2-Hydroxyethyl)-N′-methyl-thioureas.

✍ Scribed by Taek Hyeon Kim; Mi-Hyun Cha

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Efficient Synthesis of 2-Methylaminothiazolines via Mitsunobu Reaction of N-(2-Hydroxyethyl)-N'-methyl-thioureas.

-Easily available N-(2-hydroxyethyl)thioureas react under Mitsunobu conditions to yield iminothiazolidines. N-alkylated starting material gives under similar conditions a mixture of iminothiazolidines and imidazolinethiones. -(KIM,

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