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ChemInform Abstract: Efficient Syntheses of Novel C2′-Alkylated (.+-.)-K252a Analogues.

✍ Scribed by Kazuhiko Tamaki; J. Brad Shotwell; Ryan D. White; Ioana Drutu; Dejah T. Petsch; Thao V. Nheu; Hong He; Yumiko Hirokawa; Hiroshi Maruta; John L. Wood


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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Abstract

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Synthesis of Novel Isoxazolinyl Substituted Imidazo[1,2-a]pyridine C-Nucleoside Analogues. -The title isomeric C-nucleoside analogues (VI) and (IX) having hydroxymethyl-substituted isoxazoline rings in place of the ribose ring are prepared by a strategy involving cycloaddition of olefins to interme