𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Efficient One-Pot Synthesis of N-Containing Heterocycles by Multicomponent Coupling of Silicon-Tethered Diynes, Nitriles, and Isocyanides Through Intramolecular Cyclization of Iminoacyl—Zr Intermediates.

✍ Scribed by Shaoguang Zhang; Wen-Xiong Zhang; Zhenfeng Xi

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
41
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Zirconocene‐mediated multicomponent coupling of silicon‐tethered diynes, nitriles, and isocyanides results in the formation 5‐azaindoles and dihydropyrrolo[3,2‐c]azepines in dependence of the amount of isocyanides used.

📜 SIMILAR VOLUMES

Efficient One-Pot Synthesis of N-Contain
Efficient One-Pot Synthesis of N-Containing Heterocycles by Multicomponent Coupling of Silicon-Tethered Diynes, Nitriles, and Isocyanides through Intramolecular Cyclization of IminoacylZr Intermediates
✍ Shaoguang Zhang; Wen-Xiong Zhang; Zhenfeng Xi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 384 KB

## Abstract An efficient multicomponent synthesis of 5‐azaindoles and dihydropyrrolo[3,2‐__c__]azepines was achieved by zirconocene‐mediated coupling of silicon‐tethered diynes, nitriles, and isocyanides. The synthesis, structures, and intramolecular cyclization of mono‐ and bis(iminoacyl)Zr inter