ChemInform Abstract: Efficient General Asymmetric Syntheses of 3-Substituted 1(3H)- Isobenzofuranones in Very High Enantiomeric Excess.
β Scribed by P. V. RAMACHANDRAN; G.-M. CHEN; H. C. BROWN
- Book ID
- 112034346
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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The first successful asymmetric reduction of unhindered aliphatic ketones with Bchlorodiisopinocampheylborane is reported. In contrast to the reduction in high ee of aralkyl ketones, such as acetophenone, with the reagent, the reduction of unhindered dialkyl ketones, such as 3-methyl-2-butanone, pro
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