ChemInform Abstract: Efficient Differentiation of the Hydroxyl Groups of 3,4-O-Isopropylidene-D-galactopyranosides by Lipase Catalyzed Esterification and Deesterification.

✍ Scribed by P. L. BARILI; G. CATELANI; F. D'ANDREA; E. MASTRORILLI

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 34 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199804194

✦ Synopsis

Efficient Differentiation of the Hydroxyl Groups of 3,4-O-Isopropylidene-D-galactopyranosides by Lipase Catalyzed Esterification and Deesterification.

-Lipase promoted acyl transfer from vinyl acetate (II) to selected D-galactopyranosides (I) proceeds smoothly and completely site-selective in high yields. Depending on type and orientation of the aglycon, different kinds of lipase are successful. In comparable manner, efficient and highly regiospecific deacetylation reactions of 2,6-di-O-acetates (IV) are achieved.

-(BARILI,