Efficient Biomimetic-Type Synthesis of t
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Karsten Krohn; Sven Bernhard
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Article
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1999
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John Wiley and Sons
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English
โ 279 KB
๐ 1 views
Trioxo ester 15 was prepared by attachment of two vicinal C-16 regioselectively in one operation. Deprotection of 16 afforded the antibiotic G-2A (1) and decarboxylation of 1 4 and C-6 ketide side chains on the anthraquinone core (6b). Mild base treatment of 15 initiated successive aldol lead to G-2