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ChemInform Abstract: Efficient and Regioselective 9-endo Cyclization of α-Carbamoyl Radicals.

✍ Scribed by Liyan Song; Kun Liu; Chaozhong Li


Publisher
John Wiley and Sons
Year
2011
Weight
36 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The iodoalkanamide substrates undergo 9‐endo iodine transfer radical cyclization to afford an intermediate that can be converted to 9‐membered N‐heterocycles by reduction with Bu~3~SnH or to hexahydroindolizin‐ones when treated with Na~2~CO~3~.


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