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ChemInform Abstract: Efficient and Convenient C-3 Functionalization of Indoles Through Ce(OAc)3/TBHP-Mediated Oxidative C—H Bond Activation in the Presence of β-Cyclodextrin.

✍ Scribed by Yu Lin Hu; Hui Jiang; Ming Lu


Publisher
John Wiley and Sons
Year
2012
Weight
34 KB
Volume
43
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The oxidative C—H activation of indoles (I) with different alkenes and ketones in the presence of Ce(O‐Ac)~3~ and β‐cyclodextrin as catalytic system proceeds regioselectively in H~2~O to afford a variety of 3‐substituted indoles in good yields.