ChemInform Abstract: Dramatic Rate Acceleration in Titanocene Catalyzed Epoxide Openings: Cofactors and Lewis Acid Cocatalysis.

✍ Scribed by A. GANSAEUER; H. BLUHM

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 30 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199902021

✦ Synopsis

Dramatic Rate Acceleration in Titanocene Catalyzed Epoxide Openings: Cofactors and Lewis Acid Cocatalysis.

-The titanocene catalyzed addition reaction of epoxides like (I) to α,β-unsaturated carbonyl compounds can be improved by Lewis acid cocatalysis, cf. conditions A or by hydrogen bonding with cofactors such as collidine. -(GANSAEUER, A.;