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ChemInform Abstract: Discovery of Torezolid as a Novel 5-Hydroxymethyl-oxazolidinone Antibacterial Agent.

✍ Scribed by Weon Bin Im; Sun Ho Choi; Ju-Young Park; Sung Hak Choi; John Finn; Sung-Hwa Yoon

Publisher: John Wiley and Sons
Year: 2011
Weight: 21 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201128203

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✦ Synopsis

Abstract

The SAR study of a series of novel pyridyl phenyl oxazolidinone analogues leads to the discovery of title compound (I) which shows promising in vivo activity against Gram‐positive infections.

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