✦ LIBER ✦
ChemInform Abstract: Discovery of Non-Peptide, Small Molecule Antagonists of α9α10 Nicotinic Acetylcholine Receptors as Novel Analgesics for the Treatment of Neuropathic and Tonic Inflammatory Pain.
✍ Scribed by Guangrong Zheng; Zhenfa Zhang; Cheryl Dowell; Elzbieta Wala; Linda P. Dwoskin; Joseph R. Holtman; J. Michael McIntosh; Peter A. Crooks
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 25 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
A series of azaaromatic quaternary ammonium analogues, e.g. (I) and (II), is discovered as potent and selective α9α10 nicotinic acetylcholine receptor (nAChR) antagonists.