✦ LIBER ✦
ChemInform Abstract: Discovery of 4-{1-[({1- [4-(Trifluoromethyl)benzyl]-1H-indol-7-yl}carbonyl)amino] cyclopropyl}benzoic Acid (MF-766), a Highly Potent and Selective EP4 Antagonist for Treating Inflammatory Pain.
✍ Scribed by Yongxin Han; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 18 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
The synthesis of the second generation EP~4~ antagonist MF‐766 (I) is accomplished in four steps from an easily accessible methyl indolecarboxylate.