ChemInform Abstract: Discovery of 3,9-Diazabicyclo[4.2.1]nonanes as Potent Dual Orexin Receptor Antagonists with Sleep-Promoting Activity in the Rat.

✍ Scribed by Paul J. Coleman; et al. et al.

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 23 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201050173

✦ Synopsis

Abstract

The synthesis of novel constrained diazepams, e.g. (VII) (no yields given), having a bicyclic core, is described.