ChemInform Abstract: Directed ortho-Metalation Reactions of Aryl O-Carbamates: A Regiospecific Synthesis of 2,2-Disubstituted 2H-1-Benzopyrans.
β Scribed by Brian A. Chauder; Alexey V. Kalinin; Victor Snieckus
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 32 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Regioselective Directed ortho Metalation of 3H-Naphtho[2,1b]pyrans. Synthesis of Methylteretifolione B. -Treatment of naphthopyrans with tBuLi under controlled conditions results in selective ortho-metalation. Following quenching with electrophiles yields single products. The methyl derivative (II