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ChemInform Abstract: Direct and Selective N-Monoalkynylation and N-Monoalkenylation of Anilines with Alky(e)nyl Methanesulfonates Using Methylmagnesium Bromide as a Base.

✍ Scribed by Y. YOSHIDA; Y. TANABE


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Direct and Selective N-Monoalkynylation and N-Monoalkenylation of Anilines with Alky(e)nyl Methanesulfonates Using Methylmagnesium Bromide as a Base.

-Mainly N-monoalky(e)nylations take place, if anilines are treated with mesylates (II) and (IV) in the presence of MeMgBr (ratio of N-mono-:N, N-disubstituted products = 91-99:0-9). -(YOSHIDA,