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ChemInform Abstract: Dichloro(2,2,2-trifluoroethoxy)oxovanadium(V). A Remarkably Effective Reagent for Promoting One-Electron Oxidative Cyclization and Unsymmetrical Coupling of Silyl Enol Ethers.

✍ Scribed by K. RYTER; T. LIVINGHOUSE


Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Dichloro(2,2,2-trifluoroethoxy)oxovanadium(V). A Remarkably Effective Reagent for Promoting One-Electron Oxidative Cyclization and Unsymmetrical Coupling of Silyl Enol Ethers. -The new vanadium(V) ester (DTV) is superior compared to its ethoxy analogue as reagent for methylenecyclopentannulations affording compounds of type (IV) as well as unsymmetrical 1,4-diones like (IX). The importance of the allylically disposed Tms substituent in facilitating the disfavored 5-endo-trig mode during cyclization of compounds of type (III) is demonstrated with the unsilylated derivative (V). -(RYTER, K.; LIVINGHOUSE, T.;