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ChemInform Abstract: Dibenzo[b,e]azepines. Part 3. Acidic Hydrolysis.

โœ Scribed by V. G. NOSKOV; L. N. KALININA; M. N. NOSKOVA; YU. L. KRUGLYAK; A. P. BEZRUKOV; O. G. STRUKOV; V. K. KUROCHKIN

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

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Hydrolysis of 3-Chloro-2-hydroxypropylsulfamates. -Alkaline hydrolysis of the title compounds (I) provides 2,3-dihydroxypropylsulfamates (II) via epoxide intermediates. Acid hydrolysis of the product sulfamates (II) gives 3-aminopropanediols ( III) in high yields. -(TARTAKOVSKII, V. A.;